Search on: BAND 2 PROTEIN 
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Descriptor English:   Talin 
Descriptor Spanish:   Talina 
Descriptor Portuguese:   Talina 
Synonyms English:   Band 2 Protein
Platelet Protein p235
Protein p235, Platelet
Protein, Band 2  
Tree Number:   D12.776.220.985
Definition English:   A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton. 
Indexing Annotation English:   a cytoplasmic protein; /drug eff /ultrastruct permitted
History Note English:   92; was TALIN (NM) 1984-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   29792 
Unique Identifier:   D016608 

Occurrence in VHL:
 

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